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Practitioner Multivitamin Comparison

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Four major criteria may be used for evaluation of premium multivitamins in the medical marketplace. A summary is listed below the table.

  • Quality Ingredients
  • Value
  • Compliance
  • Independent Rating

Comparison

The latest (6th) edition of the Comparative Guide to Nutritional Supplements rated 1,600 multivitamins in North, South, and Central America.  A multivitamin tends to be the premier product from each brand, reflecting their sophistication in formulation and up-to-date or obsolete science.  Listed below are the highest rated products from each practitioner brand.  This table lists the contents of the manufacturer's recommended daily dose and other published information.
 

Rejuvenation Science® Maximum Vitality® Douglas Labs® Ultra Preventive® X DaVinci® Metabolic Multi Designs for Health® Complete Multi™  Thorne Research EXOS/Multi Vitamin Elite Pure Encapsulations® Polyphenol Nutrients ProThera® MultiThera® 1,2,3 Metagenics® Multigenics® Intensive Care Ortho Molecular® Alpha Base Vital Nutrients Multinutrients 2,3,5 Allergy Research Group® Multi-Vi-Min® Comments
# pills per day 2 or 4 8 6 6 6 6 6 6 4 4 - 6 1  
MSRP Price per month $45.98-48.98 $76.60 $64.40 $49.80 $59.99 $48.80 $35.95 $42.49 $26.20 $36.20 - 38.30 $5.76  
2017 Comparative Guide rating 5 4 3.5 3.5 3.5 3.5 3 3 2.5 2.5 1.5 new focus on nutrients for longevity, cell signaling, transcription factors
2017 Comparative Guide medal Gold - - - - - - - - - - manufacturing quality
2014 Comparative Guide rating 5 5 NR 4.5 4 NR 4.5 5 4.5 4 2 new findings on vitamin D3 & iodine
2007 Comparative Guide rating 5 5 NR 3 3.5 NR 4 3.5 4.5 3.5 2 new research on inflammation, oxidative stress, degenerative diseases
2003 Comparative Guide rating 100* 95.4 NR NR 46.9 NR NR 51 NR NR 18.7 *2004 update after publication, NR = not rated
Available at internet discounters no yes yes yes yes yes yes yes yes yes yes  
Premium Ingredients                        
Coenzyme Q10 20 mg 0 0 0 0 0 0 0 0 0 0 expensive, assists ATP production
trans-Resveratrol 20 mg 0 25 mg 0 0 0 0 0 0 0 0 lifespan support
alpha- & R-Lipoic Acid 100 mg 50 mg 150 mg 10 mg 0 100 mg 0 0 0 0 0 expensive, universal antioxidant
Vitamin E Tocopherol Complex 67 mg * 0 300 mg 48 mg 0 ^ 100.5 mg 50 mg 0 0 new research demonstrates important benefits of these expensive natural forms of Vitamin E.  *included but amount not specified.
Vitamin E Tocotrienols 10 mg 0 0 0 0 0 0 0 0 0 0
Vitamin K-2 180 mcg 45 mcg 100 mcg 50 mcg 200 mcg 0 20 mcg 0 62.5 mcg@ 0 0 longevity via cell signaling protein activation, enabling bone, artery, heart support
N-Acetyl Cysteine 0 mg 150 mg 0 0 0 100 mg 0 0 0 0 0 glutathione support, gene expression modulator
Green Tea Extract 70 mg 50 mg ^ 0 75 mg 100 mg 0 0 0 0 0 immune system
Milk Thistle 60 mg 0 0 0 0 0 0 0 0 0 0 liver health
Choline & PC 75 mg 60 mg 100 mg 100 mg 150 mg 100 mg 150 mg 94 mg 50 mg 0 0 structural integrity, cell membrane signaling, neurotransmission
Inositol 100 mg 100 mg 125 mg 100 mg 0 125 mg 50 mg 90 mg 50 mg 0 0 signaling and secondary messenger molecules for bone, nerve, genetic expression
DMAE 30 mg 0 0 0 0 0 0 0 0 0 0 brain and muscle support
Grape Seed Extract (Proanthocyanadins) 30 mg 50 mg 0 0 0 50 mg 0 0 0 0 0 from grape seed, red wine and pine bark
MSM 25 mg 0 0 0 0 0 0 0 0 0 0 skin, hair & muscle support
Turmeric 25 mg 0 ^ 0 200 mg 0 0 0 0 0 0 immune system, liver
Hawthorn 25 mg 0 0 0 0 0 0 0 0 0 0 heart benefits
N-Acetyl-L-Tyrosine 25 mg 0 0 0 0 0 0 0 0 0 0 brain support
Quercetin 25 mg 100 mg 0 25 mg 0 50 mg 0 19 mg 0 0 0 heart and endurance support
Ginkgo Leaf 20 mg 0 0 0 0 0 0 0 0 0 0 for microcirculation
Bilberry 5 mg ^ 0 0 0 100 mg 0 0 0 0 0 vision
Lycopene 3 mg 6 mg 1.25 mg 0 0 0 0 0 0 0 0 blood pressure
Lutein 2 mg 10 mg 6 mg 0 900 mcg 6 mg 0 ^ 0 0 0 vision
Boron 2 mg 3 mg 2 mg 2 mg 3 mg 2 mg 2 mg 0 1.5 mg 1.5 mg 200 mcg bone health, hormone management
Black Pepper Extract 3 mg 0 0 0 0 0 0 0 0 0 0 enhances micronutrient absorption
Betaine 75 mg 100 mg 0 200 mg 0 0 0 131 mg 0 0 0 liver function, cellular reproduction, metabolize homocysteine
PABA/Taurine 0 50 mg 300 mg 0 0 0 50 mg 37.5 mg 0 0 40 mg  
Base/other herbals 0 1,540 mg^ 425 mg^ 0 0 151 mg 100 mg 4 mg^ 0 0 0 vegetable, fruit, herb, green food base
Other minor components yes yes yes yes yes yes yes yes yes yes yes rutin, astaxanthin, zeaxanthin, bromelain, glutamic acid, L-methionine, etc.
Standard Ingredients                        
Vitamin A 2,500 IU 5,000 IU 1,750 IU 0 2,400 IU 0 2,500 IU 1,125 IU 0* 0 2,000 IU Higher Beta Carotene:Vitamin A ratio is preferred.  Beta Carotene is converted to Vitamin A as needed with no toxic build-up.  *Doesn't specify breakdown.
Beta Carotene 12,500 IU 10,000 IU 1,750 IU 7,142 IU 3,600 IU 7,500 IU 15,000 IU 6,375 IU 7,500 IU* 20,000 IU 0
Vitamin C 500 mg 1,000 mg 620 mg 600 mg 400 mg 500 mg 1,200 mg 900 mg 500 mg 850 mg 30 mg  
Vitamin D-3 2,000 IU 1,000 IU 2,000 IU 1,000 IU 2,500 IU 800 IU 1,000 IU 300 IU 1,000 IU 1,000 IU 100 IU  
Vitamin E (d-alpha tocopherol) 30 IU 400 IU 100 IU 50 IU 40 IU 100 IU 400 IU 150 IU 100 IU 400 IU 80 IU+ Other forms of E are listed above; saturating receptors with d-alpha blocks other tocopherols & tocotrienols
Thiamin (vitamin B-1) 50 mg 100 mg 25 mg 75 mg 50 mg 50 mg 100 mg 22.5 mg 25 mg 40 mg 20 mg  
Riboflavin (vitamin B-2) 50 mg 50 mg 37.5 mg 75 mg 12 mg 37.5 mg 50 mg 25.5 mg 25 mg 15 mg 10 mg  
Niacin & Niacinamide 50 mg 190 mg 75 mg 75 mg 60 mg 75 mg 200 mg 315 mg 25 mg 110 mg 30 mg  
Iron 0 0 0 0 0 0 0-20 mg 0 0 0 0 multivitamins should contain no iron
Vitamin B-6 50 mg 100 mg 25 mg 50 mg 20 mg 25 mg 50 mg 30 mg 37 mg 15 mg 31 mg  
Folate (methylated) 400 mcg 800 mcg 800 mcg 400 mcg# 1,000 mcg 800 mcg 800 mcg 600 mcg 400 mcg 400 mcg 60 mcg # not methylated
Vitamin B-12 (methylated) 500 mcg 250 mcg 500 mcg 500 mcg 600 mcg 500 mcg 200 mcg 150 mcg 500 mcg 500 mcg 80 mcg # not methylated
Biotin 150 mcg 300 mcg 3,000 mcg 500 mcg 1,000 mcg 800 mcg 300 mcg 150 mcg 200 mcg 400 mcg 80 mcg  
Pantothenic Acid (Vitamin B-5) 50 mg 500 mg 50 mg 250 mg 45 mg 50 mg 400 mg 150 mg 150 mg 350 mg 100 mg  
Calcium 61 mg 420 mg 150 mg 100 mg 88 mg 300 mg 253 mg 375 mg 100 mg 300 mg 20 mg increasing concern that high dose calcium buffers simultaneous dosing of other micronutrients
Iodine 100 mcg 200 mcg 200 mcg 200 mcg 150 mcg 200 mcg 150 mcg 114 mcg 112 mcg 225 mcg 0  
Magnesium 100 mg 420 mg 150 mg 200 mg 170 mg 150 mg 200 mg 187.5 mg 200 mg 275 mg 20 mg  
Zinc 15 mg 25 mg 15 mg 25 mg 30 mg 15 mg 15 mg 15.5 mg 10 mg 15 mg 6 mg  
Selenium 100 mcg 200 mcg 70 mcg 250 mcg 200 mcg 200 mcg 200 mcg 150 mcg 100 mcg 200 mcg 40 mcg  
Copper 100 mcg 2 mg 2 mg 0 1.5 mg 2 mg 0-2 mg 1.5 mg 1 mg 2 mg 0 increasing concerns about toxicity
Manganese 3 mg 9 mg 2 mg 1 mg 3 mg 5 mg 2 mg 0.75 mg 2 mg 6 mg 3 mg  
Chromium 100 mcg 200 mcg 400 mcg 200 mcg 400 mcg 100 mcg 200 mcg 150 mcg 200 mcg 200 mcg 80 mcg  
Molybdenum 100 mcg 100 mcg 0 100 mcg 100 mcg 100 mcg 150 mcg 78 mcg 25 mcg 100 mcg 40 mcg  
Potassium 50 mg 100 mg 50 mg 100 mg 0 99 mg 0 74 mg 50 mg 75 mg 20 mg  
Data from manufacturers websites August 2017               *<50% Is Vit A   +as synthetic DL-alpha tocopherol
^unidentified quantity in base                 @ <50% is K2   Wholly Immune powder is no longer in Comparative Guide
Brand and product names are trademarks of their respective manufacturers. 
 

Quality Ingredients:

Most of these practitioner brands use quality ingredients in the standard multivitamin components, such as the methylcobalamin form of Vitamin B-12, the D-3 form of Vitamin D, and a mix of various forms of minerals utilizing the amino acid chelate or krebs cycle form of the mineral for greater absorption.

Maximum Vitality® includes a number of expensive ingredients not included in the competitive offerings. These include Coenzyme Q10, trans-Resveratrol, alpha- and r-lipoic acid, the gamma tocopherol and tocotrienol forms of vitamin E, and proanthocyanidins from grape seed. Many of the ingredients in prophylactic doses are included to balance and enhance overall health. These dosages are not intended to cure disease or patients with serious deficiencies.

See Quality at Rejuvenation Science for more information.

Value

With the lowest price per month compared to lesser, 4-Star-rated multivitamins, your patients will be pleased in your choice of Maximum Vitality as the greatest value for your patients.

Compliance

Compliance is perhaps the most critical confounding factor. For if the patient is required to follow too difficult a dosing protocol, and ends up not taking their multivitamin, then no matter how high the quality, the unused supplements provide no value. Maximum Vitality provides the greatest opportunity for compliance with a dose of only 2-4 tablets per day.

Independent Rating

Confirming the sophisticated formulation and quality ingredients, Lyle MacWilliam's 2017 6th edition of the Comparative Guide to Nutritional Supplements assigned Rejuvenation Science® Maximum Vitality® the only top 5-Star rating among practitioner brands. Past editions show Maximum Vitality rating 5-Stars in the 2014 and 2007 editions, and 100 in an update to their 2003 edition, the only practitioner brand multivitamin to demonstrate ongoing enhancements to maintain a top rating for over 14 years.