CoQ10 & Carnitine Protect Liver Against Chronic Alcohol Abuse

This investigation was conducted to ascertain whether administration of L-carnitine and coenzyme Q10 could protect from the experimentally-induced hepatic lipid infiltration and glutathione content decrease in rats exposed to hyperbaric oxygen and prolonged alcohol administration.

The results indicate that administration of L-carnitine and coenzyme Q10 in association reduces damage induced by chronic alcohol poisoning and hyperbaric oxygen.

This protective action is more marked when L-carnitine and coenzyme Q10 are administered together. The combined complementary biochemical activity of these two compounds is discussed.

Source

Bertelli A, Cerrati A, Giovannini L, Mian M, Spaggiari P, Bertelli AA. Protective action of L-carnitine and coenzyme Q10 against hepatic triglyceride infiltration induced by hyperbaric oxygen and ethanol. Drugs Exp Clin Res. 1993;19(2):65-8.

Key concepts: coenzyme Q10, l-carnitine, alcohol abuse, liver damage