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Vitamin D Deficiency Associated with Chronic Pain and Obesity

Dear Doctor,

Researchers at the Mayo Clinic reported in March that vitamin D deficiency is associated with chronic pain. Researchers at the University of Minnesota reported that Vitamin D deficiency is associated with obesity. These two studies, and many others, suggest a growing deficiency in Vitamin D and the results are debilitating, yet remarkably easy to remedy.

A study published this month by researchers at Mount Sinai School of Medicine found that the cost of medications for diabetic patients ranges from $428 to $642 per month depending on where they shop. Someone pays this cost, even if the patient is only paying $180/month (at $20/prescription co-pay) for an average 8.9 medications per patient. And I suppose the patient is destined to continue on this regime for the remainder of their life. This cost of diabetes does not include physician visits, amputations, dialysis, the cost of lost work due to blindness, or other costs associated with the disease.

My message is that a healthy lifestyle, including sophisticated supplements, may be presented to your patients as a great investment in their future health and financial well-being. These studies provide the science and these statistics provide the impetus for your patients to invest in their health as if their life depended on it™. Patients report increased energy, reduction in minor aches and pains and heightened mood using our basic supplement recommendation of Maximum Vitality® multivitamin, Biom3ga™ Krill Oil, Ubiquinol and Vitamin D3K2. With simple blood tests, you can demonstrate improvement in hs-CRP, 25(OH)D, LDL, HDL, triglycerides, blood pressure and other tangible health measures for long-term benefit.

In the past, we have presented information on GlucoOptimizer™, which safely and naturally helps to normalize blood sugar levels. It has shown to reduce blood glucose levels an average of 30 – 38% after 30 days usage, narrowing the daily oscillations of blood glucose, and providing enhanced glucose transport for a faster return to normal levels. Researchers project that over years, this should help prevent the multiple long-term adverse affects of excess blood sugar.

We have Vitamin D available as D3K2 or by itself. My preference is D3K2 which also helps accrue calcium to the bones rather than soft tissue. While the plasma 25(OH)D test is relatively expensive, vitamin D3 supplementation is very inexpensive. Emerging science suggests a minimum plasma vitamin D level needed to reduce disease risk is 30 ng/mL and supplementation of 2,000 – 3,000 IU/day of the D3 form of the vitamin to achieve that level. A summary of Vitamin D research may be found here.

Below are details on the various studies. Further information is available by following the links. Please feel free to call me directly for more information.

Best Regards,

Howard Simon

Howard Simon, President

Rejuvenation Science

811 N. Catalina Ave., Suite 3208

Redondo Beach, CA 90277

888-73-REJUV (888-737-3588) +1-310-798-2830 ext 802


Sophisticated supplements for medical professionals!


Chronic pain associated with low Vitamin D - Mar 2009

Mayo Clinic research shows a correlation between inadequate vitamin D levels and the amount of narcotic medication taken by patients who have chronic pain. This correlation is an important finding as researchers discover new ways to treat chronic pain. According to the Centers for Disease Control and Prevention, chronic pain is the leading cause of disability in the United States. These patients often end up taking narcotic-type pain medication such as morphine, fentanyl or oxycodone.

This study found that patients who required narcotic pain medication, and who also had inadequate levels of vitamin D, were taking much higher doses of pain medication — nearly twice as much — as those who had adequate levels. Similarly, these patients self-reported worse physical functioning and worse overall health perception. In addition, a correlation was noted between increasing body mass index (a measure of obesity) and decreasing levels of vitamin D.

Successful weight loss with dieting is linked to vitamin D levels - Jun 2009

Vitamin D levels in the body at the start of a low-calorie diet predict weight loss success, a new study found. The results, which suggest a possible role for vitamin D in weight loss, were presented at The Endocrine Society’s 91st Annual Meeting in Washington, D.C.

The authors found that baseline, or pre-diet, vitamin D levels predicted weight loss in a linear relationship. For every increase of 1 ng/mL in level of 25-hydroxycholecalciferol—the precursor form of vitamin D and a commonly used indicator of vitamin D status—subjects ended up losing almost a half pound (0.196 kg) more on their calorie-restricted diet. For each 1-ng/mL increase in the active or “hormonal” form of vitamin D (1,25-dihydroxycholecalciferol), subjects lost nearly one-quarter pound (0.107 kg) more.

Sample Diabetes Articles

It costs a minimum of $5,200 per year to be diabetic - Aug 2008

Low vitamin D associated with 98% higher diabetes risk - Jun 2007

Three-quarters of youths with diabetes insufficient in vitamin D - Jan 2009

Vitamin D reduces risk of type 1 diabetes - Jun 2008

This information is provided for the use of physicians and other licensed health care practitioners only – to use as a basis for determining whether or not to recommend these products to their patients. This medical and scientific information is not for use by consumers. These statements have not been evaluated by the Food and Drug Administration. The dietary supplement products offered by Rejuvenation Science® are not intended for use by consumers as a means to diagnose, treat, prevent or cure any disease. ©2009 Rejuvenation Science